Effects of curcumin and luteolin on viability and cell death induction in NFS-60 cell line

  • Anja Haveric University of Sarajevo - Institute for Genetic Engineering and Biotechnology
  • Sejla Goletic University of Sarajevo - Faculty of science
  • Selma Durgut University of Sarajevo - Faculty of science
  • Maida Hadzic University of Sarajevo - Institute for Genetic Engineering and Biotechnology
  • Sanin Haveric University of Sarajevo - Institute for Genetic Engineering and Biotechnology

Abstract

Inducing cell death in tumor cells has been recognized as a promising strategy in curing tumors. Parallely, natural products, especially those with long-known usage in folk medicine, are gaining demanding and extensive clinical interests. Aiming to contribute to overall knowledge of curcumin and luteolin antitumour potentials, we analyzed their effects on cell death induction in NFS-60 cell line, using Trypan blue exclusion assay and TransDetect® Anenexin V-EGFP/PI assay. Results show that both tested agents induce cell death, especially in higher applied concentrations, but further investigations are needed to elucidate the mechanisms behind it.

Published
2018-12-25
How to Cite
HAVERIC, Anja et al. Effects of curcumin and luteolin on viability and cell death induction in NFS-60 cell line. Genetics & Applications, [S.l.], v. 2, n. 2, p. 43-50, dec. 2018. ISSN 2566-431X. Available at: <http://www.genapp.ba/index.php/genapp/article/view/58>. Date accessed: 21 aug. 2019. doi: https://doi.org/10.31383/ga.vol2iss2pp43-50.
Section
Research Articles